BRD4 is a Histone Acetyltransferase that Evicts Nucleosomes from Chromatin

Bromodomain protein 4 (BRD4) is a chromatin-binding protein implicated in cancer and autoimmune diseases that functions as a scaffold for transcription factors at promoters and super-enhancers. Whereas chromatin de-compaction and transcriptional activation of target genes are associated with BRD4 bi...

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Bibliografske podrobnosti
izdano v:Nat Struct Mol Biol
Main Authors: Devaiah, Ballachanda N., Case-Borden, Chanelle, Gegonne, Anne, Hsu, Chih Hao, Chen, Qingrong, Meerzaman, Daoud, Dey, Anup, Ozato, Keiko, Singer, Dinah S.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899182/
https://ncbi.nlm.nih.gov/pubmed/27159561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3228
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