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Talin dissociates from RIAM and associates to vinculin sequentially in response to the actomyosin force

Cells reinforce adhesion strength and cytoskeleton anchoring in response to the actomyosin force. The mechanical stretching of talin, which exposes cryptic vinculin-binding sites, triggers this process. The binding of RIAM to talin could regulate this mechanism. However, the mechanosensitivity of th...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Vigouroux, Clémence, Henriot, Véronique, Le Clainche, Christophe
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305319/
https://ncbi.nlm.nih.gov/pubmed/32561773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16922-1
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