Integrin-bound talin head inhibits actin filament barbed-end elongation

Focal adhesions (FAs) mechanically couple the extracellular matrix to the dynamic actin cytoskeleton, via transmembrane integrins and actin-binding proteins. The molecular mechanisms by which protein machineries control force transmission along this molecular axis (i.e. modulating integrin activatio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Ciobanasu, Corina, Wang, Hong, Henriot, Véronique, Mathieu, Cécile, Fente, Annabelle, Csillag, Sandrine, Vigouroux, Clémence, Faivre, Bruno, Le Clainche, Christophe
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2018
Pynciau:
Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818192/
https://ncbi.nlm.nih.gov/pubmed/29276177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.808204
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