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The role of MDM2–p53 axis dysfunction in the hepatocellular carcinoma transformation

Liver cancer is the second most frequent cause of cancer-related death globally. The main histological subtype is hepatocellular carcinoma (HCC), which is derived from hepatocytes. According to the epidemiologic studies, the most important risk factors of HCC are chronic viral infections (HBV, HCV,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Discov
Hauptverfasser: Cao, Hui, Chen, Xiaosong, Wang, Zhijun, Wang, Lei, Xia, Qiang, Zhang, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305227/
https://ncbi.nlm.nih.gov/pubmed/32595984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0287-y
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