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Relevance of the p53–MDM2 axis to aging
In response to varying stress signals, the p53 tumor suppressor is able to promote repair, survival, or elimination of damaged cells – processes that have great relevance to organismal aging. Although the link between p53 and cancer is well established, the contribution of p53 to the aging process i...
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| Published in: | Cell Death Differ |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5729541/ https://ncbi.nlm.nih.gov/pubmed/29192902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.187 |
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