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Relevance of the p53–MDM2 axis to aging

In response to varying stress signals, the p53 tumor suppressor is able to promote repair, survival, or elimination of damaged cells – processes that have great relevance to organismal aging. Although the link between p53 and cancer is well established, the contribution of p53 to the aging process i...

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Bibliografiske detaljer
Udgivet i:Cell Death Differ
Main Authors: Wu, Danyi, Prives, Carol
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729541/
https://ncbi.nlm.nih.gov/pubmed/29192902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.187
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