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The role of MDM2–p53 axis dysfunction in the hepatocellular carcinoma transformation

Liver cancer is the second most frequent cause of cancer-related death globally. The main histological subtype is hepatocellular carcinoma (HCC), which is derived from hepatocytes. According to the epidemiologic studies, the most important risk factors of HCC are chronic viral infections (HBV, HCV,...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Cao, Hui, Chen, Xiaosong, Wang, Zhijun, Wang, Lei, Xia, Qiang, Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305227/
https://ncbi.nlm.nih.gov/pubmed/32595984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0287-y
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