Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51-depleted ovarian cancer cells

Ovarian cancer is the most lethal gynecological malignancy. Abnormal homologous recombination repair, high level of reactive oxygen species (ROS) and upregulation of antioxidant genes are characteristic features of ovarian cancer. However, the molecular mechanisms governing the redox homeostasis in...

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Detaylı Bibliyografya
Yayımlandı:Redox Biol
Asıl Yazarlar: Xu, Limei, Wu, Tingting, Lu, Shihua, Hao, Xiaohe, Qin, Junchao, Wang, Jing, Zhang, Xiyu, Liu, Qiao, Kong, Beihua, Gong, Yaoqin, Liu, Zhaojian, Shao, Changshun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303666/
https://ncbi.nlm.nih.gov/pubmed/32554304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101604
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