Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51-depleted ovarian cancer cells

Ovarian cancer is the most lethal gynecological malignancy. Abnormal homologous recombination repair, high level of reactive oxygen species (ROS) and upregulation of antioxidant genes are characteristic features of ovarian cancer. However, the molecular mechanisms governing the redox homeostasis in...

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Опубликовано в: :Redox Biol
Главные авторы: Xu, Limei, Wu, Tingting, Lu, Shihua, Hao, Xiaohe, Qin, Junchao, Wang, Jing, Zhang, Xiyu, Liu, Qiao, Kong, Beihua, Gong, Yaoqin, Liu, Zhaojian, Shao, Changshun
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303666/
https://ncbi.nlm.nih.gov/pubmed/32554304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101604
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