Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51

Artesunate, a semi-synthetic derivative of arteminisin originally developed for the treatment of malaria, has recently been shown to possess antitumor properties. One of the cytotoxic effects of artesunate on cancer cells is mediated by induction of oxidative stress and DNA double-strand breaks (DSB...

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Bibliografiske detaljer
Udgivet i:Cancer Biol Ther
Main Authors: Wang, Bingliang, Hou, Dong, Liu, Qiao, Wu, Tingting, Guo, Haiyang, Zhang, Xiyu, Zou, Yongxin, Liu, Zhaojian, Liu, Jinsong, Wei, Jianjun, Gong, Yaoqin, Shao, Changshun
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391513/
https://ncbi.nlm.nih.gov/pubmed/26176175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1071738
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