Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51

Artesunate, a semi-synthetic derivative of arteminisin originally developed for the treatment of malaria, has recently been shown to possess antitumor properties. One of the cytotoxic effects of artesunate on cancer cells is mediated by induction of oxidative stress and DNA double-strand breaks (DSB...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Biol Ther
Prif Awduron: Wang, Bingliang, Hou, Dong, Liu, Qiao, Wu, Tingting, Guo, Haiyang, Zhang, Xiyu, Zou, Yongxin, Liu, Zhaojian, Liu, Jinsong, Wei, Jianjun, Gong, Yaoqin, Shao, Changshun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2015
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391513/
https://ncbi.nlm.nih.gov/pubmed/26176175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1071738
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