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Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51
Artesunate, a semi-synthetic derivative of arteminisin originally developed for the treatment of malaria, has recently been shown to possess antitumor properties. One of the cytotoxic effects of artesunate on cancer cells is mediated by induction of oxidative stress and DNA double-strand breaks (DSB...
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| Udgivet i: | Cancer Biol Ther |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391513/ https://ncbi.nlm.nih.gov/pubmed/26176175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1071738 |
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