Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51

Artesunate, a semi-synthetic derivative of arteminisin originally developed for the treatment of malaria, has recently been shown to possess antitumor properties. One of the cytotoxic effects of artesunate on cancer cells is mediated by induction of oxidative stress and DNA double-strand breaks (DSB...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Wang, Bingliang, Hou, Dong, Liu, Qiao, Wu, Tingting, Guo, Haiyang, Zhang, Xiyu, Zou, Yongxin, Liu, Zhaojian, Liu, Jinsong, Wei, Jianjun, Gong, Yaoqin, Shao, Changshun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391513/
https://ncbi.nlm.nih.gov/pubmed/26176175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1071738
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