Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51-depleted ovarian cancer cells

Ovarian cancer is the most lethal gynecological malignancy. Abnormal homologous recombination repair, high level of reactive oxygen species (ROS) and upregulation of antioxidant genes are characteristic features of ovarian cancer. However, the molecular mechanisms governing the redox homeostasis in...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Xu, Limei, Wu, Tingting, Lu, Shihua, Hao, Xiaohe, Qin, Junchao, Wang, Jing, Zhang, Xiyu, Liu, Qiao, Kong, Beihua, Gong, Yaoqin, Liu, Zhaojian, Shao, Changshun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303666/
https://ncbi.nlm.nih.gov/pubmed/32554304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101604
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