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T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers
Recent efforts toward an HIV vaccine focus on inducing broadly neutralizing antibodies, but eliciting both neutralizing antibodies (nAbs) and cellular responses may be superior. Here, we immunized macaques with an HIV envelope trimer, either alone to induce nAbs, or together with a heterologous vira...
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| Gepubliceerd in: | Nat Med |
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| Hoofdauteurs: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group US
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7303014/ https://ncbi.nlm.nih.gov/pubmed/32393800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-020-0858-8 |
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