Clade C HIV-1 Envelope Vaccination Regimens Differ in Their Ability To Elicit Antibodies with Moderate Neutralization Breadth against Genetically Diverse Tier 2 HIV-1 Envelope Variants

The goals of preclinical HIV vaccine studies in nonhuman primates are to develop and test different approaches for their ability to generate protective immunity. Here, we compared the impact of 7 different vaccine modalities, all expressing the HIV-1 1086.C clade C envelope (Env), on (i) the magnitu...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Burton, Samantha, Spicer, Lori M., Charles, Tysheena P., Gangadhara, Sailaja, Reddy, Pradeep B. J., Styles, Tiffany M., Velu, Vijayakumar, Kasturi, Sudhir Pai, Legere, Traci, Hunter, Eric, Pulendran, Bali, Amara, Rama, Hraber, Peter, Derdeyn, Cynthia A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430525/
https://ncbi.nlm.nih.gov/pubmed/30651354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01846-18
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