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Discovery, development, and future application of senolytics: theories and predictions

Senescent cells accumulate with aging and at etiological sites of multiple diseases, including those accounting for most morbidity, mortality, and health costs. Senescent cells do not replicate, can release factors that cause tissue dysfunction, and yet remain viable. The discovery of senolytic drug...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Wissler Gerdes, Erin O., Zhu, Yi, Tchkonia, Tamar, Kirkland, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302972/
https://ncbi.nlm.nih.gov/pubmed/32112672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15264
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