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The Clinical Potential of Senolytic Drugs

Senolytic drugs are agents that selectively induce apoptosis of senescent cells. These cells accumulate in many tissues with aging and at sites of pathology in multiple chronic diseases. In studies in animals, targeting senescent cells using genetic or pharmacological approaches delays, prevents, or...

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Detalhes bibliográficos
Publicado no:J Am Geriatr Soc
Main Authors: Kirkland, James L., Tchkonia, Tamara, Zhu, Yi, Niedernhofer, Laura J., Robbins, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641223/
https://ncbi.nlm.nih.gov/pubmed/28869295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jgs.14969
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