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Clinical Strategies and Animal Models for Developing Senolytic Agents

Aging is associated with increasing predisposition to multiple chronic diseases. One fundamental aging process that is often operative at sites of the pathology underlying chronic age-related diseases is cellular senescence. Small molecule senolytic agents are being developed. For successful drug de...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Kirkland, James L., Tchkonia, Tamara
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412760/
https://ncbi.nlm.nih.gov/pubmed/25446976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.10.012
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