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Senolytic drugs: from discovery to translation
Senolytics are a class of drugs that selectively clear senescent cells (SC). The first senolytic drugs Dasatinib, Quercetin, Fisetin and Navitoclax were discovered using a hypothesis‐driven approach. SC accumulate with ageing and at causal sites of multiple chronic disorders, including diseases acco...
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| Veröffentlicht in: | J Intern Med |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7405395/ https://ncbi.nlm.nih.gov/pubmed/32686219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joim.13141 |
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