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Distance-Based Metrics for Comparing Conformational Ensembles of Intrinsically Disordered Proteins

Intrinsically disordered proteins are proteins whose native functional states represent ensembles of highly diverse conformations. Such ensembles are a challenge for quantitative structure comparisons because their conformational diversity precludes optimal superimposition of the atomic coordinates...

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Bibliografiska uppgifter
I publikationen:Biophys J
Huvudupphovsmän: Lazar, Tamas, Guharoy, Mainak, Vranken, Wim, Rauscher, Sarah, Wodak, Shoshana J., Tompa, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7300341/
https://ncbi.nlm.nih.gov/pubmed/32502383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.05.015
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