Distance-Based Metrics for Comparing Conformational Ensembles of Intrinsically Disordered Proteins

Intrinsically disordered proteins are proteins whose native functional states represent ensembles of highly diverse conformations. Such ensembles are a challenge for quantitative structure comparisons because their conformational diversity precludes optimal superimposition of the atomic coordinates...

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Vydáno v:Biophys J
Hlavní autoři: Lazar, Tamas, Guharoy, Mainak, Vranken, Wim, Rauscher, Sarah, Wodak, Shoshana J., Tompa, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7300341/
https://ncbi.nlm.nih.gov/pubmed/32502383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.05.015
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