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The balancing act of intrinsically disordered proteins: enabling functional diversity while minimizing promiscuity

Intrinsically disordered proteins (IDPs) or regions (IDRs) perform diverse cellular functions, but are also prone to forming promiscuous and potentially deleterious interactions. We investigate the extent to which the properties of, and content in, IDRs have adapted to enable functional diversity wh...

詳細記述

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書誌詳細
出版年:J Mol Biol
主要な著者: Macossay-Castillo, Mauricio, Marvelli, Giulio, Guharoy, Mainak, Jain, Aashish, Kihara, Daisuke, Tompa, Peter, Wodak, Shoshana J.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453724/
https://ncbi.nlm.nih.gov/pubmed/30878482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.03.008
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