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The balancing act of intrinsically disordered proteins: enabling functional diversity while minimizing promiscuity

Intrinsically disordered proteins (IDPs) or regions (IDRs) perform diverse cellular functions, but are also prone to forming promiscuous and potentially deleterious interactions. We investigate the extent to which the properties of, and content in, IDRs have adapted to enable functional diversity wh...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Macossay-Castillo, Mauricio, Marvelli, Giulio, Guharoy, Mainak, Jain, Aashish, Kihara, Daisuke, Tompa, Peter, Wodak, Shoshana J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453724/
https://ncbi.nlm.nih.gov/pubmed/30878482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.03.008
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