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The Insulinostatic Effect of Ghrelin Requires MRAP2 Expression in δ Cells

Ghrelin regulates both energy intake and glucose homeostasis. In the endocrine pancreas, ghrelin inhibits insulin release to prevent hypoglycemia during fasting. The mechanism through which this is accomplished is unclear, but recent studies suggest that ghrelin acts on δ cells to stimulate somatost...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Yin, Terry C., Bauchle, Casey J., Rouault, Alix A.J., Stephens, Samuel B., Sebag, Julien A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7300157/
https://ncbi.nlm.nih.gov/pubmed/32535024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101216
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