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Structure and Function of the Melanocortin2 Receptor Accessory Protein MRAP
The melanocortin2 (MC2), or ACTH receptor, requires MC2 receptor accessory protein (MRAP) for function, and individuals lacking MRAP are ACTH-resistant and glucocorticoid-deficient. MRAP facilitates trafficking of the MC2 receptor to the plasma membrane and is absolutely required for ACTH binding an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677758/ https://ncbi.nlm.nih.gov/pubmed/19028547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2008.10.041 |
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