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Structure and Function of the Melanocortin2 Receptor Accessory Protein MRAP

The melanocortin2 (MC2), or ACTH receptor, requires MC2 receptor accessory protein (MRAP) for function, and individuals lacking MRAP are ACTH-resistant and glucocorticoid-deficient. MRAP facilitates trafficking of the MC2 receptor to the plasma membrane and is absolutely required for ACTH binding an...

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Sonraí Bibleagrafaíochta
Main Authors: Hinkle, Patricia M., Sebag, Julien A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677758/
https://ncbi.nlm.nih.gov/pubmed/19028547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2008.10.041
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