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Melanocortin-2 receptor accessory protein MRAP forms antiparallel homodimers

The melanocortin-2 (MC2) receptor accessory protein (MRAP) is required for trafficking of the G protein-coupled MC2 receptor to the plasma membrane. The mechanism of action and structure of MRAP, which has a single transmembrane domain, are unknown. Here, we show that MRAP displays a previously unch...

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Autors principals: Sebag, Julien A., Hinkle, Patricia M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154416/
https://ncbi.nlm.nih.gov/pubmed/18077336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708916105
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