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MRAP2 regulates ghrelin receptor signaling and hunger sensing

Ghrelin is the only known circulating orexigenic hormone. It is primarily secreted by the stomach and acts at its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), in the hypothalamus to signal hunger and promote food intake. The melanocortin receptor accessory protein 2 (MRAP2) was pr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Srisai, Dollada, Yin, Terry C., Lee, Abigail A., Rouault, Alix A. J., Pearson, Nicole A., Grobe, Justin L., Sebag, Julien A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620068/
https://ncbi.nlm.nih.gov/pubmed/28959025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00747-6
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