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MRAP2 regulates ghrelin receptor signaling and hunger sensing

Ghrelin is the only known circulating orexigenic hormone. It is primarily secreted by the stomach and acts at its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), in the hypothalamus to signal hunger and promote food intake. The melanocortin receptor accessory protein 2 (MRAP2) was pr...

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Publicado en:Nat Commun
Autores principales: Srisai, Dollada, Yin, Terry C., Lee, Abigail A., Rouault, Alix A. J., Pearson, Nicole A., Grobe, Justin L., Sebag, Julien A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620068/
https://ncbi.nlm.nih.gov/pubmed/28959025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00747-6
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