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MRAP2 regulates ghrelin receptor signaling and hunger sensing

Ghrelin is the only known circulating orexigenic hormone. It is primarily secreted by the stomach and acts at its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), in the hypothalamus to signal hunger and promote food intake. The melanocortin receptor accessory protein 2 (MRAP2) was pr...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Srisai, Dollada, Yin, Terry C., Lee, Abigail A., Rouault, Alix A. J., Pearson, Nicole A., Grobe, Justin L., Sebag, Julien A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620068/
https://ncbi.nlm.nih.gov/pubmed/28959025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00747-6
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