Urupocidin C: a new marine guanidine alkaloid which selectively kills prostate cancer cells via mitochondria targeting

New bicyclic guanidine alkaloid, urupocidin C (Ur-C) along with the previously known urupocidin A (Ur-A) were isolated from the rare deep-sea marine sponge Monanchora pulchra, harvested in Northwestern Pacific waters. The unique structure of Ur-C was elucidated using 1D and 2D NMR spectroscopy as we...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Dyshlovoy, Sergey A., Kudryashova, Ekaterina K., Kaune, Moritz, Makarieva, Tatyana N., Shubina, Larisa K., Busenbender, Tobias, Denisenko, Vladimir A., Popov, Roman S., Hauschild, Jessica, Fedorov, Sergey N., Bokemeyer, Carsten, Graefen, Markus, Stonik, Valentin A., von Amsberg, Gunhild
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299949/
https://ncbi.nlm.nih.gov/pubmed/32555282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66428-5
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