Urupocidin C: a new marine guanidine alkaloid which selectively kills prostate cancer cells via mitochondria targeting

New bicyclic guanidine alkaloid, urupocidin C (Ur-C) along with the previously known urupocidin A (Ur-A) were isolated from the rare deep-sea marine sponge Monanchora pulchra, harvested in Northwestern Pacific waters. The unique structure of Ur-C was elucidated using 1D and 2D NMR spectroscopy as we...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Dyshlovoy, Sergey A., Kudryashova, Ekaterina K., Kaune, Moritz, Makarieva, Tatyana N., Shubina, Larisa K., Busenbender, Tobias, Denisenko, Vladimir A., Popov, Roman S., Hauschild, Jessica, Fedorov, Sergey N., Bokemeyer, Carsten, Graefen, Markus, Stonik, Valentin A., von Amsberg, Gunhild
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299949/
https://ncbi.nlm.nih.gov/pubmed/32555282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66428-5
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