Urupocidin C: a new marine guanidine alkaloid which selectively kills prostate cancer cells via mitochondria targeting

New bicyclic guanidine alkaloid, urupocidin C (Ur-C) along with the previously known urupocidin A (Ur-A) were isolated from the rare deep-sea marine sponge Monanchora pulchra, harvested in Northwestern Pacific waters. The unique structure of Ur-C was elucidated using 1D and 2D NMR spectroscopy as we...

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書誌詳細
出版年:Sci Rep
主要な著者: Dyshlovoy, Sergey A., Kudryashova, Ekaterina K., Kaune, Moritz, Makarieva, Tatyana N., Shubina, Larisa K., Busenbender, Tobias, Denisenko, Vladimir A., Popov, Roman S., Hauschild, Jessica, Fedorov, Sergey N., Bokemeyer, Carsten, Graefen, Markus, Stonik, Valentin A., von Amsberg, Gunhild
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299949/
https://ncbi.nlm.nih.gov/pubmed/32555282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66428-5
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