Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer

Development of resistance to standard therapies complicates treatment of advanced prostate cancer. Alternative splicing variants of the androgen receptor (AR), e.g. AR-V7 can mediate resistance to AR-targeting substances abiraterone and enzalutamide. Semi-synthetic marine natural compound rhizochali...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dyshlovoy, Sergey A., Otte, Katharina, Tabakmakher, Kseniya M., Hauschild, Jessica, Makarieva, Tatyana N., Shubina, Larisa K., Fedorov, Sergey N., Bokemeyer, Carsten, Stonik, Valentin A., von Amsberg, Gunhild
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908298/
https://ncbi.nlm.nih.gov/pubmed/29682197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24764
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