Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer

Development of resistance to standard therapies complicates treatment of advanced prostate cancer. Alternative splicing variants of the androgen receptor (AR), e.g. AR-V7 can mediate resistance to AR-targeting substances abiraterone and enzalutamide. Semi-synthetic marine natural compound rhizochali...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Dyshlovoy, Sergey A., Otte, Katharina, Tabakmakher, Kseniya M., Hauschild, Jessica, Makarieva, Tatyana N., Shubina, Larisa K., Fedorov, Sergey N., Bokemeyer, Carsten, Stonik, Valentin A., von Amsberg, Gunhild
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908298/
https://ncbi.nlm.nih.gov/pubmed/29682197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24764
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