Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer

Development of drug resistance is an inevitable phenomenon in castration-resistant prostate cancer (CRPC) cells requiring novel therapeutic approaches. In this study, efficacy and toxicity of Rhizochalinin (Rhiz) – a novel sphingolipid-like marine compound – was evaluated in prostate cancer models,...

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Vydáno v:Oncotarget
Hlavní autoři: Dyshlovoy, Sergey A., Otte, Katharina, Alsdorf, Winfried H., Hauschild, Jessica, Lange, Tobias, Venz, Simone, Bauer, Christiane K., Bähring, Robert, Amann, Kerstin, Mandanchi, Ramin, Schumacher, Udo, Schröder-Schwarz, Jennifer, Makarieva, Tatyana N., Guzii, Alla G., Tabakmakher, Kseniya M., Fedorov, Sergey N., Shubina, Larisa K., Kasheverov, Igor E., Ehmke, Heimo, Steuber, Thomas, Stonik, Valentin A., Bokemeyer, Carsten, Honecker, Friedemann, von Amsberg, Gunhild
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342509/
https://ncbi.nlm.nih.gov/pubmed/27626485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11941
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