Urupocidin C: a new marine guanidine alkaloid which selectively kills prostate cancer cells via mitochondria targeting

New bicyclic guanidine alkaloid, urupocidin C (Ur-C) along with the previously known urupocidin A (Ur-A) were isolated from the rare deep-sea marine sponge Monanchora pulchra, harvested in Northwestern Pacific waters. The unique structure of Ur-C was elucidated using 1D and 2D NMR spectroscopy as we...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dyshlovoy, Sergey A., Kudryashova, Ekaterina K., Kaune, Moritz, Makarieva, Tatyana N., Shubina, Larisa K., Busenbender, Tobias, Denisenko, Vladimir A., Popov, Roman S., Hauschild, Jessica, Fedorov, Sergey N., Bokemeyer, Carsten, Graefen, Markus, Stonik, Valentin A., von Amsberg, Gunhild
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299949/
https://ncbi.nlm.nih.gov/pubmed/32555282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66428-5
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