Hydrated electrons induce the formation of interstrand cross-links in DNA modified by cisplatin adducts

Double-stranded oligonucleotides containing cisplatin adducts, with and without a mismatched region, were exposed to hydrated electrons generated by gamma-rays. Gel electrophoresis analysis demonstrates the formation of cisplatin-interstrand crosslinks from the cisplatin-intrastrand species. The rat...

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Detalhes bibliográficos
Publicado no:J Radiat Res
Main Authors: Behmand, B, Noronha, A M, Wilds, C J, Marignier, J-L, Mostafavi, M, Wagner, J R, Hunting, D J, Sanche, L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Regular Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299263/
https://ncbi.nlm.nih.gov/pubmed/32211848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rraa014
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