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Hydrated Electrons React with High Specificity with Cisplatin Bound to Single-Stranded DNA

[Image: see text] Short oligonucleotides TTTTTGTGTTT and TTTTTTTGTTT in solution with and without cisplatin (cisPt) bound to the guanine bases were irradiated with γ-rays at doses varying from 0 to 2500 Gy. To determine the effect of hydrated electrons from water radiolysis on the oligonucleotides,...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Behmand, B., Cloutier, P., Girouard, S., Wagner, J. R., Sanche, L., Hunting, D. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623754/
https://ncbi.nlm.nih.gov/pubmed/24205952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp4089904
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