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Cisplatin Intrastrand Adducts Sensitize DNA to Base Damage by Hydrated Electrons

[Image: see text] The oligonucleotide TTTTTGTGTTT with or without a cisplatin adduct was reacted with hydrated electrons generated by ionizing radiation. Hydroxyl radicals were quenched with ethylenediaminetetraacetic acid (EDTA), and the solutions were bubbled with wet nitrogen to eliminate oxygen,...

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Vydáno v:J Phys Chem B
Hlavní autoři: Behmand, B., Wagner, J. R., Sanche, L., Hunting, D. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623755/
https://ncbi.nlm.nih.gov/pubmed/24779712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp5014913
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