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Radiosensitization of DNA by Cisplatin Adducts Results from an Increase in the Rate Constant for the Reaction with Hydrated Electrons and Formation of Pt(I)

[Image: see text] Pulse radiolysis measurements of the decay of hydrated electrons in solutions containing different concentrations of the oligonucleotide GTG with and without a cisplatin adduct show that the presence of a cisplatin moiety accelerates the reaction between hydrated electrons and the...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Behmand, B., Marignier, J.-L., Mostafavi, M., Wagner, J. R., Hunting, D. J., Sanche, L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623752/
https://ncbi.nlm.nih.gov/pubmed/26098937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b01752
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