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Cisplatin Radiosensitization of DNA Irradiated with 2–20 eV Electrons: Role of Transient Anions

Platinum chemotherapeutic agents, such as cisplatin (cis-diamminedichloroplatinum(II)), can act as radiosensitizers when bound covalently to nuclear DNA in cancer cells. This radiosensitization is largely due to an increase in DNA damage induced by low-energy secondary electrons, produced in large q...

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Bibliographic Details
Published in:J Phys Chem C Nanomater Interfaces
Main Authors: Bao, Qianhong, Chen, Yunfeng, Zheng, Yi, Sanche, Léon
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716812/
https://ncbi.nlm.nih.gov/pubmed/26793285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp503706h
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