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Cisplatin Radiosensitization of DNA Irradiated with 2–20 eV Electrons: Role of Transient Anions
Platinum chemotherapeutic agents, such as cisplatin (cis-diamminedichloroplatinum(II)), can act as radiosensitizers when bound covalently to nuclear DNA in cancer cells. This radiosensitization is largely due to an increase in DNA damage induced by low-energy secondary electrons, produced in large q...
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| Pubblicato in: | J Phys Chem C Nanomater Interfaces |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4716812/ https://ncbi.nlm.nih.gov/pubmed/26793285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp503706h |
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