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Single-step electronic detection of femtomolar DNA by target-induced strand displacement in an electrode-bound duplex

We report a signal-on, electronic DNA (E-DNA) sensor that is label-free and achieves a subpicomolar detection limit. The sensor, which is based on a target-induced strand displacement mechanism, is composed of a “capture probe” attached by its 5′ terminus to a gold electrode and a 5′ methylene blue-...

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Detalhes bibliográficos
Main Authors: Xiao, Yi, Lubin, Arica A., Baker, Brian R., Plaxco, Kevin W., Heeger, Alan J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1622927/
https://ncbi.nlm.nih.gov/pubmed/17065320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607693103
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