Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion

Understanding complex tissues requires single-cell deconstruction of gene regulation with precision and scale. Here, we assess the performance of a massively parallel droplet-based method for mapping transposase-accessible chromatin in single cells using sequencing (scATAC-seq). We apply scATAC-seq...

Full description

Saved in:
Bibliographic Details
Published in:Nat Biotechnol
Main Authors: Satpathy, Ansuman T., Granja, Jeffrey M., Yost, Kathryn E., Qi, Yanyan, Meschi, Francesca, McDermott, Geoffrey P., Olsen, Brett N., Mumbach, Maxwell R., Pierce, Sarah E., Corces, M. Ryan, Shah, Preyas, Bell, Jason C., Jhutty, Darisha, Nemec, Corey M., Wang, Jean, Wang, Li, Yin, Yifeng, Giresi, Paul G., Chang, Anne Lynn S., Zheng, Grace X. Y., Greenleaf, William J., Chang, Howard Y.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299161/
https://ncbi.nlm.nih.gov/pubmed/31375813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0206-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items