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Potential Contribution of Ryanodine Receptor 2 Upregulation to cGMP/PKG Signaling-induced Cone Degeneration in Cyclic Nucleotide-gated Channel Deficiency
Photoreceptor cyclic nucleotide-gated (CNG) channels regulate Ca(2+) influx in rod and cone photoreceptors. Mutations in cone CNG channel subunits CNGA3 and CNGB3 are associated with achromatopsia and cone dystrophies. Mice lacking functional cone CNG channel show endoplasmic reticulum (ER) stress-a...
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| 出版年: | FASEB J |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7299158/ https://ncbi.nlm.nih.gov/pubmed/32173907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901951RR |
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