Ryanodine Receptor 2 Contributes to Impaired Protein Localization in Cyclic Nucleotide-Gated Channel Deficiency

The photoreceptor cyclic nucleotide-gated (CNG) channel plays a pivotal role in phototransduction and cellular calcium homeostasis. Mutations in the cone photoreceptor CNG channel subunits CNGA3 and CNGB3 are associated with achromatopsia and cone dystrophies. CNG channel deficiency leads to endopla...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Ma, Hongwei, Yang, Fan, Butler, Michael R., Rapp, Jacob, Le, Yun-Zheng, Ding, Xi-Qin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597858/
https://ncbi.nlm.nih.gov/pubmed/31182474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0119-19.2019
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