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Endoplasmic reticulum (ER) Ca(2+)-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency

Endoplasmic reticulum (ER) stress and mislocalization of improperly folded proteins have been shown to contribute to photoreceptor death in models of inherited retinal degenerative diseases. In particular, mice with cone cyclic nucleotide-gated (CNG) channel deficiency, a model for achromatopsia, di...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Butler, Michael R., Ma, Hongwei, Yang, Fan, Belcher, Joshua, Le, Yun-Zheng, Mikoshiba, Katsuhiko, Biel, Martin, Michalakis, Stylianos, Iuso, Anthony, Križaj, David, Ding, Xi-Qin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500788/
https://ncbi.nlm.nih.gov/pubmed/28495882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.782326
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