Endoplasmic reticulum (ER) Ca(2+)-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency

Endoplasmic reticulum (ER) stress and mislocalization of improperly folded proteins have been shown to contribute to photoreceptor death in models of inherited retinal degenerative diseases. In particular, mice with cone cyclic nucleotide-gated (CNG) channel deficiency, a model for achromatopsia, di...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Butler, Michael R., Ma, Hongwei, Yang, Fan, Belcher, Joshua, Le, Yun-Zheng, Mikoshiba, Katsuhiko, Biel, Martin, Michalakis, Stylianos, Iuso, Anthony, Križaj, David, Ding, Xi-Qin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2017
Gaiak:
Molecular Bases of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500788/
https://ncbi.nlm.nih.gov/pubmed/28495882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.782326
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