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Endoplasmic reticulum (ER) Ca(2+)-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency
Endoplasmic reticulum (ER) stress and mislocalization of improperly folded proteins have been shown to contribute to photoreceptor death in models of inherited retinal degenerative diseases. In particular, mice with cone cyclic nucleotide-gated (CNG) channel deficiency, a model for achromatopsia, di...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5500788/ https://ncbi.nlm.nih.gov/pubmed/28495882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.782326 |
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