The Glutamic Acid-Rich Protein Is a Gating Inhibitor of Cyclic Nucleotide-Gated Channels

The cyclic nucleotide-gated (CNG) cation channel of rod photoreceptors is a heterotetramer consisting of homologous CNGA1 and CNGB1a subunits. While CNGA1 is indispensable for channel activation, the specific role of CNGB1a in this process has remained elusive. Here, we show that the N-terminal glut...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Michalakis, Stylianos, Zong, Xiangang, Becirovic, Elvir, Hammelmann, Verena, Wein, Thomas, Wanner, Klaus T., Biel, Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622767/
https://ncbi.nlm.nih.gov/pubmed/21209198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4735-10.2011
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