The Glutamic Acid-Rich Protein Is a Gating Inhibitor of Cyclic Nucleotide-Gated Channels

The cyclic nucleotide-gated (CNG) cation channel of rod photoreceptors is a heterotetramer consisting of homologous CNGA1 and CNGB1a subunits. While CNGA1 is indispensable for channel activation, the specific role of CNGB1a in this process has remained elusive. Here, we show that the N-terminal glut...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Michalakis, Stylianos, Zong, Xiangang, Becirovic, Elvir, Hammelmann, Verena, Wein, Thomas, Wanner, Klaus T., Biel, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622767/
https://ncbi.nlm.nih.gov/pubmed/21209198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4735-10.2011
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