Nalaganje...

The cGMP-Dependent Protein Kinase II Is an Inhibitory Modulator of the Hyperpolarization-Activated HCN2 Channel

Opening of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels is facilitated by direct binding of cyclic nucleotides to a cyclic nucleotide-binding domain (CNBD) in the C-terminus. Here, we show for the first time that in the HCN2 channel cGMP can also exert an inhibitory effect on g...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Hammelmann, Verena, Zong, Xiangang, Hofmann, Franz, Michalakis, Stylianos, Biel, Martin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038938/
https://ncbi.nlm.nih.gov/pubmed/21347269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017078
Oznake: Označite
Brez oznak, prvi označite!