Wordt geladen...

The cGMP-Dependent Protein Kinase II Is an Inhibitory Modulator of the Hyperpolarization-Activated HCN2 Channel

Opening of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels is facilitated by direct binding of cyclic nucleotides to a cyclic nucleotide-binding domain (CNBD) in the C-terminus. Here, we show for the first time that in the HCN2 channel cGMP can also exert an inhibitory effect on g...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Hammelmann, Verena, Zong, Xiangang, Hofmann, Franz, Michalakis, Stylianos, Biel, Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038938/
https://ncbi.nlm.nih.gov/pubmed/21347269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017078
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!