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Nitric oxide activates hypoglossal motoneurons by cGMP-dependent inhibition of TASK channels and cGMP-independent activation of HCN channels

Nitric oxide (NO) is an important signaling molecule that regulates numerous physiological processes, including activity of respiratory motoneurons. However, molecular mechanism(s) underlying NO modulation of motoneurons remain obscure. Here, we used a combination of in vivo and in vitro recording t...

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Main Authors: Wenker, Ian C., Benoit, Justin P., Chen, Xinnian, Liu, Hattie, Horner, Richard L., Mulkey, Daniel K.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311688/
https://ncbi.nlm.nih.gov/pubmed/22131386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00827.2011
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