Ryanodine Receptor 2 Contributes to Impaired Protein Localization in Cyclic Nucleotide-Gated Channel Deficiency

The photoreceptor cyclic nucleotide-gated (CNG) channel plays a pivotal role in phototransduction and cellular calcium homeostasis. Mutations in the cone photoreceptor CNG channel subunits CNGA3 and CNGB3 are associated with achromatopsia and cone dystrophies. CNG channel deficiency leads to endopla...

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Vydáno v:eNeuro
Hlavní autoři: Ma, Hongwei, Yang, Fan, Butler, Michael R., Rapp, Jacob, Le, Yun-Zheng, Ding, Xi-Qin
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2019
Témata:
New Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597858/
https://ncbi.nlm.nih.gov/pubmed/31182474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0119-19.2019
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