Levosimendan Protects against Doxorubicin-Induced Cardiotoxicity by Regulating the PTEN/Akt Pathway

BACKGROUND AND AIMS: Myocyte apoptosis plays a critical role in the development of doxorubicin- (DOX-) induced cardiotoxicity. In addition to its cardiotonic effect, laboratory evidence indicates that levosimendan can inhibit apoptosis, but its role in DOX-induced cardiac injury remains unclear. The...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biomed Res Int
Main Authors: Li, Ling-Li, Wei, Li, Zhang, Ning, Wei, Wen-Ying, Hu, Can, Deng, Wei, Tang, Qi-Zhu
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7298255/
https://ncbi.nlm.nih.gov/pubmed/32596387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8593617
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