Pioglitazone Protected against Cardiac Hypertrophy via Inhibiting AKT/GSK3β and MAPK Signaling Pathways

Peroxisome proliferator activated receptor γ (PPARγ) has been closely involved in the process of cardiovascular diseases. This study was to investigate whether pioglitazone (PIO), a PPARγ agonist, could protect against pressure overload-induced cardiac hypertrophy. Mice were orally given PIO (2.5 mg...

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Detalhes bibliográficos
Publicado no:PPAR Res
Main Authors: Wei, Wen-Ying, Ma, Zhen-Guo, Xu, Si-Chi, Zhang, Ning, Tang, Qi-Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826695/
https://ncbi.nlm.nih.gov/pubmed/27110236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9174190
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