Oridonin protects against cardiac hypertrophy by promoting P21-related autophagy

Autophagy is an endogenous protective process; the loss of autophagy could destabilize proteostasis and elevate intracellular oxidative stress, which is critically involved in the development of cardiac hypertrophy and heart failure. Oridonin, a natural tetracycline diterpenoid from the Chinese herb...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Xu, Man, Wan, Chun-xia, Huang, Si-hui, Wang, Hui-bo, Fan, Di, Wu, Hai-Ming, Wu, Qing-qing, Ma, Zhen-guo, Deng, Wei, Tang, Qi-Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534559/
https://ncbi.nlm.nih.gov/pubmed/31127082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1617-y
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