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Oridonin protects against cardiac hypertrophy by promoting P21-related autophagy
Autophagy is an endogenous protective process; the loss of autophagy could destabilize proteostasis and elevate intracellular oxidative stress, which is critically involved in the development of cardiac hypertrophy and heart failure. Oridonin, a natural tetracycline diterpenoid from the Chinese herb...
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| Publié dans: | Cell Death Dis |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6534559/ https://ncbi.nlm.nih.gov/pubmed/31127082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1617-y |
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