Corosolic acid ameliorates cardiac hypertrophy via regulating autophagy

Aim: In this work, we explored the role of corosolic acid (CRA) during pressure overload-induced cardiac hypertrophy. Methods and results: Cardiac hypertrophy was induced in mice by aortic banding. Four weeks post-surgery, CRA-treated mice developed blunted cardiac hypertrophy, fibrosis, and dysfunc...

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Bibliografske podrobnosti
izdano v:Biosci Rep
Main Authors: Wang, Zhao-Peng, Shen, Difei, Che, Yan, Jin, Ya-Ge, Wang, Sha-Sha, Wu, Qing-Qing, Zhou, Heng, Meng, Yan-Yan, Yuan, Yuan
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2019
Teme:
Cardiovascular System & Vascular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893168/
https://ncbi.nlm.nih.gov/pubmed/31746323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20191860
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