Suppression of calcium-sensing receptor ameliorates cardiac hypertrophy through inhibition of autophagy

The calcium-sensing receptor (CaSR) releases intracellular calcium ([Ca(2+)](i)) by accumulating inositol phosphate. Changes in [Ca(2+)](i) initiate myocardial hypertrophy. Furthermore, autophagy associated with [Ca(2+)](i). Autophagy has previously been demonstrated to participate in the hypertroph...

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Vydáno v:Mol Med Rep
Hlavní autoři: LIU, LEI, WANG, CHAO, LIN, YAN, XI, YUHUI, LI, HONG, SHI, SA, LI, HONGZHU, ZHANG, WEIHUA, ZHAO, YAJUN, TIAN, YE, XU, CHANGQING, WANG, LINA
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2016
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918534/
https://ncbi.nlm.nih.gov/pubmed/27176663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5279
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