Protection against cardiac hypertrophy by geniposide involves the GLP‐1 receptor / AMPKα signalling pathway

BACKGROUND AND PURPOSE: Activation of glucagon‐like peptide‐1 (GLP‐1) receptor exerts a range of cardioprotective effects. Geniposide is an agonist of GLP‐1 receptor, but its role in cardiac hypertrophy remains completely unknown. Here, we have investigated its protective effects and clarified the u...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Ma, Zhen‐Guo, Dai, Jia, Zhang, Wen‐Bin, Yuan, Yuan, Liao, Hai‐Han, Zhang, Ning, Bian, Zhou‐Yan, Tang, Qi‐Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831312/
https://ncbi.nlm.nih.gov/pubmed/26845648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13449
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