Protection against cardiac hypertrophy by geniposide involves the GLP‐1 receptor / AMPKα signalling pathway

BACKGROUND AND PURPOSE: Activation of glucagon‐like peptide‐1 (GLP‐1) receptor exerts a range of cardioprotective effects. Geniposide is an agonist of GLP‐1 receptor, but its role in cardiac hypertrophy remains completely unknown. Here, we have investigated its protective effects and clarified the u...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: Ma, Zhen‐Guo, Dai, Jia, Zhang, Wen‐Bin, Yuan, Yuan, Liao, Hai‐Han, Zhang, Ning, Bian, Zhou‐Yan, Tang, Qi‐Zhu
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831312/
https://ncbi.nlm.nih.gov/pubmed/26845648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13449
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